Benefits Of Lion's Mane Mushroom For Dogs

Benefits Of Lion's Mane Mushroom For Dogs

Improved nerve and brain function are among the many benefits of Lion's Mane mushroom for dogs. But you’ll find many more reasons to give your dog this medicinal mushroom with exceptional healing benefits.

Let’s look at the benefits of Lion's Mane mushroom for dogs … and why it’s called nature’s nutrient for the neurons.

Top Benefits Of Lion's Mane Mushroom For Dogs

Lion's Mane is known for its top benefits. This mushroom can support brain, gut and heart health, slow the process of paralysis, and prevent and manage cancer. Here’s more detail on what Lion's Mane can do for your dog.

Brain And Neurological Support

Studies show Lion's Mane can stimulate nerve growth and help regenerate damaged nerves. 

That is welcome news to those who have senior dogs. Just like people, senior dogs can get doggie dementia. You might see your dog get disoriented or lost in his own house. Lion's Mane can help. Plus, giving Lion's Mane to younger dogs can help prevent problems in later years. 

These studies confirm that Lion's Mane can aid brain function and memory. 

  • In a 2004 Japanese study measured improved functional capacity in patients with mild dementia
  • Participants showed improvement in a 2009 Japanese study … but results declined when the Lion's Mane supplement stopped (1) 
  • Another study found that Lion's Mane extracts were able to pass through the blood/brain barrier to stimulate the production of nerve growth factor (NGF) (2). 
  • This 2017 study showed Lions Mane prevented the impairment of short-term and visual recognition memory when tested in mice (3).

Low NGF appears in diseases like Alzheimer’s and dementia. When NGF is present in higher amounts, it helps neurons in the brain survive. 

May Help With Degenerative Myelopathy

Dogs with degenerative myelopathy (DM) (similar to MS or Multiple Sclerosis in humans) slowly lose mobility and become paralyzed in their rear legs. In DM, your dog’s immune system attacks the myelin sheath that protects nerve fibers in the central nervous system. That prevents nerves from transmitting messages to and from the brain. And that leads to nerve damage and loss of control. 

Lion's Mane has been found to help stimulate myelinization after myelin damage (4). 

Fights Cancer 

Studies show that Lion's Mane is another medicinal mushroom that can slow, reverse or prevent cancer. It’s had an effect on leukemia and cancers of the stomach, lungs, liver and colon. It’s also been shown to cause apoptosis (cancer cell death) (5).

A 2013 study is noteworthy for extracts from Lion's Mane to inhibit metastasis of cancer cells in mice (6). Combining Lion's Mane with Turkey Tail mushroom, another mushroom known for its cancer-fighting abilities, could be a valuable combination of supplements to give your dog.

Supports Gut Health And Immune Support

Lion's Mane supports your dog’s digestive health as a prebiotic. It feeds the beneficial bacteria in your dog’s gut to support the immune system. And there’s more research that Lion's Mane has shown immune system benefits in mice. This is important when you consider that around 90% of your dog’s immune system lives in his gut. 

Lion's Mane has the ability to help rebuild your dog’s intestinal lining as well as prevent or repair leaky gut. There are several studies showing Lion's Mane has anti-ulcer effects. Plus Lion's Mane extracts were shown to improve gastritis and inflammatory bowel disease (IBD) (7, 8). 

Improves Heart Health

Lion's Mane has the ability to reduce chronic inflammation … and that reduces stress on your dog’s heart. It’s also been found to help control obesity, which can lead to heart disease. 

Oxidative stress from free radicals can damage arteries. But Lion's Mane has antioxidant properties to limit that (9, 10). And it also has an extract that can prevent blood clotting to lower the risk of stroke.

Has Antibacterial Properties

Antibiotics kill all bacteria, bad and good … including the good bacteria in your dog’s gut that supports his immune system. Lion's Mane is a natural alternative to antibiotics to fight stubborn bacterial infections like MRSA (Methicillin-Resistant Staphylococcus Aureus). It’s antibiotic-resistant so it’s hard to get rid of. 

The canine version is MRSP … methicillin-resistant staphylococcus pseudointermedius … and it’s just as hard to treat. It can lead to wounds that don’t heal, and persistent UTIs, ear, eye and skin infections.

But studies show that it’s been able to fight infections of H. pylori and MRSA (11).

And there’s also a long history supporting the benefits of Lion's Mane mushroom as a healing mushroom.

Additional Benefits of Lion's Mane Mushroom For Dogs

Practitioners of Traditional Chinese Medicine have used Lion's Mane for thousands of years because it’s:

  • Antibiotic
  • Antioxidant
  • Anti-diabetic
  • Anti-fatigue
  • Cardioprotective
  • Anti-inflammatory
  • Anti-aging
  • Hepatoprotective for liver support
  • Nephroprotective for kidney support
  • Neuroprotective to slow the loss of neurons

FOUR LEAF ROVER RECOMMENDS: Give your dog Lion's Mane mushrooms to support his brain, nervous system and immunity. Buy Lion's Mane now >>

Today, it’s easier than ever to get Lion’s Mane mushroom for your dog.

How To Give Lion's Mane Mushroom To Dogs

First of all, you want to choose a supplement made from whole fruiting bodies. Many supplements are just mycelium ... which is higher in starch and lower in the beta-glucans that give mushrooms all those health benefits. In most of the research quoted, extracts came from whole fruiting bodies. 

And you want to ensure there are no fillers. Compare the dosing between different products and don’t be fooled by large containers that are mostly fillers.

Next, if it’s a product for dogs, follow the dosing instructions on the label. If it’s for people, assume the instructions are for a 150-lb person, then adjust for your dog’s size. 

You can also feed your dog mushrooms but you always need to cook them first. Dogs can’t digest raw mushrooms well. 

So these are some of the many benefits of Lions Mane mushrooms for dogs. Consider giving your dog Lion's Mane ... especially if he's a senior.


1. Mori K, et al. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009 Mar;23(3):367-72.

2. Lai PL, et al. Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. 2013;15(6):539-54.

3. Brandalise F, et al. Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice. Evid Based Complement Alternat Med.2017;2017:3864340.

4. Kolotushkina EV, et al. The influence of Hericium erinaceus extract on myelinization process in vitro. Fiziol Zh. 2003;49(1):38-45. PMID: 12675022.

5. Li W, et al. Isolation and identification of aromatic compounds in Lion's Mane Mushroom and their anticancer activities. Food Chem. 2015 Mar 1;170:336-42.

6. Kim SP, et al. Hericium erinaceus (Lion's Mane) mushroom extracts inhibit metastasis of cancer cells to the lung in CT-26 colon cancer-tansplanted mice. J Agric Food Chem. 2013 May 22;61(20):4898-904. 

7. Wang M, et al. Anti-Gastric Ulcer Activity of Polysaccharide Fraction Isolated from Mycelium Culture of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes). Int J Med Mushrooms. 2015;17(11):1055-60.

8. Qin M, et al. Anti-Inflammatory Effects of Ethanol Extract of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), in Mice with Ulcerative Colitis. Int J Med Mushrooms. 2016;18(3):227-34.

9. Rahman MA, Abdullah N, Aminudin N. Inhibitory effect on in vitro LDL oxidation and HMG Co-A reductase activity of the liquid-liquid partitioned fractions of Hericium erinaceus (Bull.) Persoon (lion's mane mushroom). Biomed Res Int.2014;2014:828149.

10. Kushairi, N, et al. Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. Suppresses H2O2-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia. Antioxidants. Aug 2019. Vol 8, Issue 8. 

11. Kawagishi, Hirokazu. Anti-MRSA Compounds from Hericium erinaceus (Bull.Fr.). International Journal of Medicinal Mushrooms. 2005. Vol 7, issue 3.


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